Mixed herb PHY906 may reduce the gastrointestinal toxicity from cancer chemotherapy Marketing Articles | February 21 , 2012

A mixed herb PHY906 can reduce the gastrointestinal toxicity damage from cancer chemotherapy. This study emphasizes the value of traditional herbal treatment and explains the possible therapeutic mechanisms.



Toxic side effects of anticancer drugs resveratrol is a major factor to limit Iraq irinotecan effective use, because serious side effects affecting the quality of life. Irinotecan is a DNA-isomerase inhibitor, is the second-line drugs for the treatment of colon and rectal cancer, PHY906 of mixed herbs in the effect of reducing the gastrointestinal toxicity caused by irinotecan. Diarrhea and nausea are common side effects of irinotecan, resulting in taking the drug also ulcers and intestinal bleeding [url=http://www.cheapsuperstarshoes.org/adidas-yeezy-500-utility-black-men-s-che... Yeezy 500 Utility Black Men's Cheap , because it will lead to intestinal cell death and inflammation. However, the ways to control these toxic side effects limit the efficacy of the play.


PHY906 from on one for the treatment of nausea, vomiting and diarrhea, an ancient Chinese herbal formula composed of four kinds of herbs, their quality of stability control. Now , when will be the PHY906 used to take patients with irinotecan, which can reduce the patients with diarrhea and vomiting.


In order to study the reasons for PHY906 ease irinotecan lead to intestinal damage, Yale University School of Medicine used a colorectal cancer model in mice. Irinotecan conga PHY906 such tumors in mice 4 days of treatment, results showed that PHY906 alone can inhibit tumor growth, but it can stimulate the activity of irinotecan antitumor [url=http://www.cheapsuperstarshoes.org/cheap-adidas-nmd-xr1-camo-pack-men-s-oli... Adidas NMD XR1 Camo Pack Men's Olive , and mitigation and drugs in treatment-related weight loss. In addition, PHY906 promote recovery and regeneration of the intestinal cells by the injury of irinotecan.


Further studies have shown that PHY906 can not prevent irinotecan in the intestinal cells caused by DNA damage, but it can reduce the number of apoptosis, increased intestinal cell proliferation after treatment with irinotecan. Irinotecan Kang treatment PHY906 can promote intestinal progenitor source cell or stem cell marker expression, such as a cell surface transmembrane docetaxel glycoprotein CD44 , rich in leucine repeat of the G-protein coupled receptor (LGRs) 5 and source chromosome 2 (ASCL2).


Regeneration was observed in the intestinal cells, Wnt signaling channel stimulation, because taking irinotecan after Kang the PHY906 increase the expression of key wnt components, such as Wnt3, FZD5 (frizzled 5) and low density lipoprotein by body-related protein 5. The study also showed that human embryonic liver cells [url=http://www.cheapsuperstarshoes.org/cheap-adidas-ultra-boost-uncaged-men-s-n... Adidas Ultra Boost Uncaged Men's New Black , the PHY906 of treatment increased the activity of Wnt3A. The PHY906 inhibit irinotecan stimulate inflammation in several steps. PHY906 treatment blocked the infiltration of the intestinal neutrophils and macrophages reduced the expression of precursor cells in inflammatory cytokines such as tumor necrosis factor, etc.


Thus, although PHY906 can not directly protect the intestinal system from damage caused by chemotherapy, it does stimulate rehabilitation of intestinal cells through the promotion of rebirth of the ancestral source cell and the inhibition of inflammation. This study highlights the therapeutic value of traditional herbal medicine and illustrates the potential therapeutic mechanism which regulates various biological activities through the multi-herbal formula ingredients. It may be able to provide the efficacy that conventional medicines can not achieve.Source:http:www.cospcn

Article Tags: Gastrointestinal Toxicity, Side Effects , Intestinal Cells

In the cut-throat opponents occurring over the World Wide Web these days, it is necessary to take the services of an awesome online promotion company to sustain a unique lifestyle over the web. These local seo in Waterloo Ontario will work for you under the outer lining so that you can implement your time in growing your company internet marketing. However, according to of the component that you will see most organizations when you are going to look for them, so at times it becomes a bit hard to find out the best company that suits your needs. Well, let's clear confusions by discussing about a few biggies.
Local seo in Kitchener Ontario Company knows the value of efficiently posting your company online information over the most essential on the internet directories over and above to the market and market particular websites. A excellent information your company on on the world wide web in the best classification and in the most essential on the world wide web online internet directories will help increase your positions and get more traffic to your website. There are compensated and free results to supply [url=http://www.cheapsuperstarshoes.org/adidas-ultra-boost-clima-grey-men-s-chea... Ultra Boost Clima Grey Men's Cheap , a skilled local seo in Kitchener Ontario knows which to select and which to disregard.
They will look for the appropriate search phrases of your market and select because of proper issues and low opponents to distribute them on the content of your website. Also, they will look for any technological issue that might restrict your site to be rated over search engines. Further, to provide you with better positions, they will research over the websites of your rivals who are position top over search engines and based on that, they would change your Headline manufacturers , Meta information, include web hyperlinks and other codings of the WebPages. All in all, they will make your website user and search engine friendly. If a company gives you the assurance of top identify over Google and other search engines within a certain restrict without actually looking over the chances, opportunities are very excellent they would not keep their guarantees. So, it's best to keep away from such local seo in Waterloo Ontario Company as considering the co. [url=http://www.wholesaleshoesforsale.com/]Wholesale Nike Shoes Womens Wholesale Air Jordan 2018 Wholesale Air Max Plus Wholesale Vapormax Shoes Wholesale Nike Shoes Discount Cheap Air Jordans China Wholesale Nike Shoes China Cheap Air Max Wholesale Wholesale Air Max Womens Wholesale Womens Air Max